Platelet Rich Plasma a New Prospective in Treatment of Recalcitrant Erosive Lichen Planus – A Case Report

Main Article Content

Sameeulla Shaik
P. Naga Jyothi
B. Vijay Kumar
S. V. Suman
K. Sai Praveen
Mercy Sravanthi

Abstract

Oral lichen planus(OLP) is a chronic disease that worsens the quality of life of patients with risk of malignant potential. Treatment of OLP remains a significant challenge despite the recent advances in understanding the immunopathogenesis. The properties of Platelet-rich plasma (PRP) because of its growth factors, such as epidermal growth factor (EGF), fibroblast growth factor (FGF), Transforming growth factor(TGF β1) and keratinocyte growth factor (KGF) suggested its application in clinical practice for treatment of OLP patients that do not respond to conventional therapy. Hereby we report a case of erosive OLP resistant to conventional therapy efficiently treated with PRP.

Keywords:
Oral Lichen Planus, platelet rich plasma, fibroblast growth factor.

Article Details

How to Cite
Shaik, S., Jyothi, P. N., Kumar, B. V., Suman, S. V., Praveen, K. S., & Sravanthi, M. (2020). Platelet Rich Plasma a New Prospective in Treatment of Recalcitrant Erosive Lichen Planus – A Case Report. International Journal of Research and Reports in Dentistry, 3(1), 1-5. Retrieved from http://journalijrrd.com/index.php/IJRRD/article/view/30106
Section
Case Report

References

Scully C, Beyli M, Ferreiro MC, et al. Update on oral lichen planus: Etiopathogenesis and management. Crit Rev Oral Biol Med. 1998;9:86–122.

Roopashree MR, Gondhalekar RV, Shashikanth MC, George J, Thippeswamy SH, Shukla A. Pathogenesis of oral lichen planus – A review. J Oral Pathol Med. 2010;39:729–734.

Gupta S, Ghosh S, Gupta S. Interventions for the management of oral lichen planus: A review of the conventional and novel therapies. Oral Dis. 2017;23;1029–1042.

Fornaini C. LLLT in the Symptomatic Treatment of Oral Lichen Planus. Laser Ther. 2012;21:51–53.

Pietrzak WS, Eppley BL. Scientific Foundations Platelet Rich Plasma: Biology and New Technology. The Journal of Craniofacial Surgery. 2005;16(6):1043–54.

Merigo E, Oppici A, Parlatore A, Cella L, Clini F, Fontana M, Fornaini C. Platelet-Rich Plasma (PRP) Rinses for the Treatment of Non-Responding Oral Lichen Planus: A Case Report. Biomedicines. 2018;6(1):1-4.

Eisenberg E. Oral lichen planus: a benign lesion. J Oral Maxillofac Surg. 2000; 58(11):1278-1285.

Giuliani M, Troiano G, Cordaro M, Corsalini M, Gioco G, Lo Muzio L, Pignatelli P, Lajolo C. Rate of malignant transformation of oral lichen planus: A systematic review. Oral Dis. 2019;25(3): 693-709.

Passeron T, Zakaria W, Ostovari N, Montoux F, Lacour JP, Ortonne JP. Treatment of erosive lichen planus by 308nm excimer laser. Lasers Surg Med. 2004;34 (4):205-209.

Raeissadat SA, Babaee M, Rayegani SM, Hashemi Z, Hamidieh AA, Mojgani P, Fouladi Vanda H. An overview of platelet products (PRP, PRGF, PRF, etc.) in the Iranian studies. Future Sci. 2017;3(4):231 34.

Loré B, Saraceno R, Poladas G, Fida M, Khoury C, Arcuri C, Magnato R. Oral lichen planus: therapy and phenotype. G Ital Dermatol Venereol. 2018;153(4):459-463.

El-Komy MHM, Hassan AS, Raheem HMA, Doss SS, El-Kaliouby M, Saleh NA, Saleh MA. Platelet-rich plasma for resistant oral erosions of pemphigus vulgaris: A pilot study. Wound Repair and Regeneration. 2015;23(6):953–955.