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Oral lichen planus(OLP) is a chronic disease that worsens the quality of life of patients with risk of malignant potential. Treatment of OLP remains a significant challenge despite the recent advances in understanding the immunopathogenesis. The properties of Platelet-rich plasma (PRP) because of its growth factors, such as epidermal growth factor (EGF), fibroblast growth factor (FGF), Transforming growth factor(TGF β1) and keratinocyte growth factor (KGF) suggested its application in clinical practice for treatment of OLP patients that do not respond to conventional therapy. Hereby we report a case of erosive OLP resistant to conventional therapy efficiently treated with PRP.
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