Management of Medication-related Osteonecrosis of Posterior Maxilla with Buccal Fat Pad Flap: Case Report

Main Article Content

Kagan Deniz
Firdevs Senel

Abstract

Bisphosphonates are one of the most commonly prescribed drugs in bone-associated diseases. Medication-related osteonecrosis of the jaws (MRONJ) is a new term and the common side effect of long term bisphosphonate therapy; characterized by the presence of exposed necrotic bone and non-healing mucosa. Although there has been an increasing number of MRONJ cases; it is management is still a challenge for clinicians. In this case report, the management of MRONJ with buccal fat pad flap in an osteoporotic patient is described.

Keywords:
Medication, osteonecrosis, posterior maxilla, bisphosphonate therapy.

Article Details

How to Cite
Deniz, K., & Senel, F. (2020). Management of Medication-related Osteonecrosis of Posterior Maxilla with Buccal Fat Pad Flap: Case Report. International Journal of Research and Reports in Dentistry, 3(1), 15-19. Retrieved from http://journalijrrd.com/index.php/IJRRD/article/view/30108
Section
Case Study

References

Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B. American association of oral and maxillofacial surgeons. American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw – 2014 Update. Journal of Oral and Maxillofacial Surgery. 2014;72(10):1938–1956.
Available:https://doi.org/10.1016/j.joms.2014.04.031

Favia G, Tempesta A, Limongelli L, Crincoli V, Iannone F, Lapadula G, Maiorano E. A case of osteonecrosis of the jaw in a patient with Crohn's disease treated with infliximab. Am J Case Rep. 2017;18:1351-1356.

Marx RE. Pamidronate (aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic. J Oral Maxillofac Surg. 2003;61:1115.

Pazianas M, Miller P, Blumentals WA, Bernal M, Kothawala P. A review of the literature on osteonecrosis of the jaw in patient with osteoporosis treated with oral bisphosphanates: Prevalance, risk factors, and clinical characteristics. Clin Ther. 2007;29:1548-1558.

Rizzoli R, Burlet N, Cahall D, et al. Osteonecrosis of the jaw and bisphos-phanate treatment for osteoporosis. Bone. 2008;42:841-847.

Ruggiero SL, Dodson TB, Assael LA, Landesberg R, Marx RE, Mebrotra B. American association of oral and maxillofacial surgens position paper on bisphosphanate-related osteonecrosis of the jaws-2009 update. J Oral Maxillofac Surg. 2009;67:2-12.

Hayashida S, Soutome S, Yanamoto S, Fujita S, Hasegawa T, Komori T, Umeda M. Evaluation of the treatment strategies for Medication-Related Osteonecrosis of the Jaws (MRONJ) and the factors affecting treatment outcome: A multicenter retrospective study with propensity score matching analysis. Journal of Bone and Mineral Research, Epublication ahead of Print; 2017.

Available:https://doi.org/10.1002/jbmr.3191

Ian R. Reid, Mark J. Bolland, Andrew B. Grey. Is bisphosphonate-associated osteonecrosis of the jaw caused soft tissue by toxicity? Bone. 2007;41:318–320.

Hanazawa Y, Itoh K, Mabashi T, et al. Closure of oroantral communications using a pedicled buccal fat pad graft. J Oral Maxillofac Surg. 1995;53:771.

Dean A, Alamillos F, Garcia-LoPez A, et al. The buccal fat pad flap in oral reconstruction. Head Neck. 2001;23:383.

Advisory task force on bisphosphonate-related osteonecrosis of the jaws. AAMOS: American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws. J Oral Maxillofac Surg. 2007;65: 369.

Pazianas M, Miller P, Blumentals WA, Bernal M, Kothawala P. A review of the literature on osteonecrosis of the jaw in patient with osteoporosis treated with oral bisphosphanates: Prevalance, risk factors, and clinical characteristics. Clin Ther. 2007;29:1548-1558.

Zhang MH, Yan Y, Ming Q, et al. Anatomical structure of the buccal fat pad and its clinical adaptations. Plast Reconstr Surg. 2002;109:2509.

Baumann A, Ewers E. Application of the buccal fat pad in oral reconstruction. J Oral Maxillofac Surg. 2000;58: 389.

Jackson IT. Anatomy of the buccal fat pad and its clinical significance. Plast Reconstr Surg. 1999;103:2059.

Fujimura N, Nagura H, Enomoto S. Grafting of the buccal fat pad into palatal defects. J Craniomaxillofacial Surg. 1990;18:219.