Prosthetic Rehabilitation in Carcinoma of the Tongue and Oral Pelvis: Presentation of a Clinical Case

S. Bucolo *

ENT Department, San Giovanni Bosco Hospital, Turin, Italy.

V. G. Scopelliti

UOSD Otorinolaringoiatria Policlinico Tor Vergata, Rome, Italy.

U. Visentin

ENT Department, San Giovanni Bosco Hospital, Turin, Italy.

M. V. Pomara

ENT Department, San Giovanni Bosco Hospital, Turin, Italy.

M. Pezzoli

ENT Department, San Giovanni Bosco Hospital, Turin, Italy.

C. Caldarelli

Maxillofacial Surgery Unit San Giovanni Bosco Hospital, Turin, Italy.

G. Succo

ENT Department, San Giovanni Bosco Hospital, Turin, Italy.

*Author to whom correspondence should be addressed.


Abstract

Aims: The authors want to describe a case of prosthetic rehabilitation in a 50 years old woman who has undergone a removal surgery of a neoplastic lesion that involved the oral pelvis and the lingual border. The inherent literature regarding the prosthetic rehabilitation of post-irradiated bones is also evaluated.

Presentation of Case: A 50-year-old Caucasian woman with a history of smoking and alcohol consumption has come to our attention with an ulcerative lesion of the left lingual  pelvis.

Discussion: The patient’s clinical, radiological, and anamnestic data enabled the preoperative staging of the oral cavity’s neoplasm, which has been treated with a transmandibular conservative surgical resection of the lesion associated with a mRND and bilateral neck dissection (LV. I to III); this was then followed by an immediate surgical reconstruction with a radial antebrachial bundle-cutaneous free flap.

Conclusion: One year after surgery, excluding the presence of recurrences through MR with contrast, the dental residues have been removed, and rehabilitation with an implanted prosthesis has been completed. Aesthetic outcome was remarkable. Both the preoperative multi-specialist evaluation and the definition of a common rehabilitation program represent essential prerequisites in order to avoid some possible and serious complications of the treatment. Postoperative radiotherapy for oral cancer is now universally associated with implant-prosthetic rehabilitation therapy.

Keywords: Oral cancer, forearm free flap, reconstruction, radiotherapy, oral implantology, antebrachial bundle-cutaneous free flap


How to Cite

Bucolo , S., Scopelliti , V. G., Visentin , U., Pomara , M. V., Pezzoli , M., Caldarelli , C., & Succo , G. (2023). Prosthetic Rehabilitation in Carcinoma of the Tongue and Oral Pelvis: Presentation of a Clinical Case. International Journal of Research and Reports in Dentistry, 6(2), 59–65. Retrieved from https://journalijrrd.com/index.php/IJRRD/article/view/157


References

Yang DY. Management of vascular problems in microsurgery. Zhonghua Wai Ke Za Zhi. 1981;19(3):131-135.

Soutar DS, Scheker LR, Tanner NS, McGregor IA. The radial forearm flap: a versatile method for intra-oral reconstruction. Br J Plast Surg. 1983;36(1):1-8.

Dholam KP, Gurav SV. Dental implants in irradiated jaws: a literature review. J Cancer Res Ther. 2012;8 Suppl 1:S85-93.

Nelson K, Heberer S, Glatzer C. Survival analysis and clinical evaluation of implant-retained prostheses in oral cancer resection patients over a mean follow-up period of 10 years. J Prosthet Dent. 2007;98(5):405-410.

Knospe WH, Blom J, Crosby WH. Regeneration of locally irradiated bone marrow. I. Dose dependent, long-term changes in the rat, with particular emphasis upon vascular and stromal reaction. Blood. 1966;28(3):398-415.

Colella G, Cannavale R, Pentenero M, Gandolfo S. Oral implants in radiated patients: a systematic review. Int J Oral Maxillofac Implants. 2007;22(4):616-622.

Korfage A, Schoen PJ, Raghoebar GM, Bouma J, Burlage FR, Roodenburg JL, Vissink A, Reintsema H. Five-year follow-up of oral functioning and quality of life in patients with oral cancer with implant-retained mandibular overdentures. Head Neck. 2011;33(6):831-839.

Chim H, Salgado CJ, Mardini S, Chen HC. Reconstruction of mandibular defects. Semin Plast Surg. 2010;24(2):188-197.

Claudy MP, Miguens SA Jr, Celeste RK, Camara Parente R, Hernandez PA, da Silva AN Jr. Time interval after radiotherapy and dental implant failure: systematic review of observational studies and meta-analysis. Clin Implant Dent Relat Res. 2015 Apr;17(2):402-11. DOI: 10.1111/cid.12096. Epub 2013 Jun 7. PMID: 23742098.

Shirota T, Ohno K, Michi K, Tachikawa T. An experimental study of healing around hydroxylapatite implants installed with autogenous iliac bone grafts for jaw reconstruction. J Oral Maxillofac Surg. 1991;49(12):1310-1315.

Mortensen SP, Damsgaard R, Dawson EA, Secher NH, González-Alonso J. Restrictions in systemic and locomotor skeletal muscle perfusion, oxygen supply and VO2 during high-intensity whole-body exercise in humans. J Physiol. 2008;586(10):2621-2635.

Spiegelberg L, Djasim UM, van Neck HW, Wolvius EB, van der Wal KG. Hyperbaric oxygen therapy in the management of radiation-induced injury in the head and neck region: a review of the literature. J Oral Maxillofac Surg. 2010;68(8):1732-1739.

Marx RE, Kline SN. Principles and methods of osseous reconstruction. Int Adv Surg Oncol. 1983;6:167-228.

Larsen PE. Placement of dental implants in the irradiated mandible: a protocol involving adjunctive hyperbaric oxygen. J Oral Maxillofac Surg. 1997;55(9):967-971.

Granström G. Placement of dental implants in irradiated bone: the case for using hyperbaric oxygen. J Oral Maxillofac Surg. 2006;64(5):812-818.

Benites Condezo AF, Araujo RZ, Koga DH, Curi MM, Cardoso CL. Hyperbaric oxygen therapy for the placement of dental implants in irradiated patients: systematic review and meta-analysis. Br J Oral Maxillofac Surg. 2021 Jul;59(6):625-632. DOI: 10.1016/j.bjoms.2020.08.050. Epub 2020 Aug 19. PMID: 33952404.

Shaw RJ, Butterworth CJ, Silcocks P, Tesfaye BT, Bickerstaff M, Jackson R, Kanatas A, Nixon P, McCaul J, Praveen P, Lowe T, Blanco-Guzman M, Forner L, Brennan P, Fardy M, Parkin R, Smerdon G, Stephenson R, Cope T, Glover M. HOPON (Hyperbaric Oxygen for the Prevention of Osteoradionecrosis): A randomized controlled trial of hyperbaric oxygen to prevent osteoradionecrosis of the irradiated mandible after dentoalveolar surgery. Int J Radiat Oncol Biol Phys. 2019 Jul 1;104(3):530-539. DOI: 10.1016/j.ijrobp.2019.02.044. Epub 2019 Mar 7. PMID: 30851351.

Schoen PJ, Raghoebar GM, Bouma J, Reintsema H, Vissink A, Sterk W, Roodenburg JL. Rehabilitation of oral function in head and neck cancer patients after radiotherapy with implant-retained dentures: effects of hyperbaric oxygen therapy. Oral Oncol. 2007;43(4):379- 388.

Coulthard P, Patel S, Grusovin GM, Worthington HV, Esposito M. Hyperbaric oxygen therapy for irradiated patients who require dental implants: a Cochrane review of randomised clinical trials. Eur J Oral Implantol. 2008;1(2):105-110.

Barret JP, Roodenburg JL. Functional rehabilitation in advanced intraoral cancer. Int J Surg Oncol (N Y). 2017 Feb;2(2):e10. DOI:10.1097/IJ9.0000000000000010. Epub 2017 Jan 10. PMID: 29177211; PMCID: PMC5673113.